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Each package contains four 1.2 mL syringes of refreshing Mint whitening gel for use with properly fitted dentist provided custom whitening trays or compatible retainers. Whitening trays are not included. For shoppers looking for a trusted professional teeth whitening gel, Opalescence combines more than 35 years of professional whitening experience with extensive dental research and dentist created formulations. Opalescence is the world's #1 selling professional teeth whitening brand, is trusted by more than 25,000 dentists and has helped brighten more than 150 million smiles worldwide. Opalescence is also recognized by the brand as the most researched teeth whitening brand. WHY CHOOSE OPALESCENCE 35%? The 35% carbamide peroxide formula is Opalescence's fastest treatment option among its custom tray whitening gel refills. It is designed for approximately 30 to 60 minutes of wear per treatment when used as directed and can whiten teeth up to 5 shades. Individual whitening results vary based on starting tooth shade, stain type and individual response. PROFESSIONAL FORMULA DEVELOPED FOR DENTAL WHITENING Opalescence Whitening Gel Refills feature the same formulation available through dental professionals. The active carbamide peroxide formula works beyond surface stains to help whiten discoloration caused by coffee, tea, wine, soda, tobacco and other common sources of tooth staining. GENTLE ON ENAMEL Professional strength does not mean abrasive whitening. Opalescence custom tray whitening gel uses nonabrasive ingredients and is formulated to whiten gently and effectively while remaining gentle on enamel. The 35% formula contains potassium nitrate for added comfort while whitening and also contains fluoride and xylitol. 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